The sunbird Syn (TM) assay accurately classified Parkinson's disease-positive blood samples with 81% accuracy through the direct detection of EV-bound aggregated alpha-synuclein proteins -- -- With no ...

Key proteins implicated in neurodegenerative diseases are alpha synuclein and tau. Tau aggregation into neurofibrillary tangles, along with amyloid-beta aggregation into plaques, is a hallmark of ...

A rare genetic variant reveals mitochondria can kick-start Parkinson’s, linking oxidative stress to alpha-synuclein clumps ...

Amsterdam, NL, November 13, 2019 - Aggregates of the protein alpha-synuclein arising in the gut may play a key role in the development of Parkinson's disease (PD). Investigators are testing the ...

Millions of people in the United States are affected by Parkinson’s disease and Lewy Body Dementia (LBD). These are both ...

Studies have uncovered that abnormalities in the alpha-synuclein protein are likely a causal factor for numerous diseases, including Parkinson’s disease, multiple system atrophy (MSA), dementia with ...

In the brain, alpha-synuclein is known for forming clumps called Lewy bodies, which damage brain cells and lead to diseases ...

Multiple system atrophy (MSA) is a neurodegenerative disorder characterized by the aggregation of alpha-synuclein in the brain. Now, scientists have developed a radioligand that facilitates the ...

The small molecule spermine has the potential to stop the toxic build-up of proteins in the brain that characterizes diseases like Alzheimer's and Parkinson's, researchers have found – and it works a ...