Panelists discuss how amyloid-targeting therapies for Alzheimer disease represent a breakthrough drug class that works by binding to and removing beta-amyloid plaques through various mechanisms, ...

Prof. Liu Cong from the Shanghai Institute of Organic Chemistry of the Chinese Academy of Sciences, along with collaborators, ...

Pernilla Wittung-Stafshede, the Charles W. Duncan Jr.-Welch Chair in Chemistry and the executive director of the Amyloid Mechanism and Disease Center (Credit: Gustavo Raskosky/Rice University). Rice ...

New study reveals how the ketone body β-hydroxybutyrate can halt toxic protein buildup, paving the way for innovative therapies against Alzheimer's and aging-related brain dysfunction. Study: ...

Lecanemab (Lequembi, Esai), an amyloid beta–directed antibody therapy, is approved by the US Food and Drug Administration (FDA) for the treatment of Alzheimer's disease (AD). But exactly how the drug ...

Researchers headed by a team at the Centre for Genomic Regulation, Barcelona Institute of Science and Technology and at the Wellcome Sanger Institute have developed an AI tool that they say has made a ...

Researchers have identified a backup mechanism of protein quality control which prevents the toxic effects of protein aggregation in specific tissues when normal methods of molecular monitoring fail.