Statistical methods now being used in adaptive biomarker-driven clinical trials are reviewed. Some previous paradigms for clinical trial design can limit the development of more effective methods on ...

Faculty in the Medical Devices and Diagnostics Hub develop statistical methods for the design, evaluation, and validation of diagnostic tools and medical devices. Their work includes biomarker ...

Faculty in this hub lead the design, coordination, and analysis of clinical trials for cancer treatment, survivorship, vaccine efficacy, infectious disease prevention and treatment, and cancer ...

Despite recent advances in cancer precision medicine, patients from underserved communities do not have equal access to biomarker testing and targeted therapies. This study used a mixed-methods ...

Biomarker research has made substantial progress recently beyond the proverbial low-hanging fruit. Emerging technologies and techniques are helping make biomarker detection and application faster, ...

New exploratory findings demonstrate that in responders with IGFBP7 biomarker decline, CNM-Au8 30mg was strongly associated ...

This population-based study shows that shared and pattern-specific blood biomarkers reflect biological vulnerability ...