A new study by Scripps Research reveals that alcohol dependence disrupts two signaling pathways in a stress-related part of the brain—and offers insights on developing drugs to treat this condition.

Addiction is one of the most intensely studied conditions in modern medicine, yet even with high‑resolution brain scans and ...

Gene therapy ‘switch’ may offer non-addictive pain relief. New approach targets pain signals while leaving the rest of the brain untouched.

Inflammation and mitochondrial function as mechanisms in accelerated aging (AA) across substance use disorders (SUDs). This figure presents a proposed model linking genes associated with ...

Addiction is a disease that affects millions of Americans. It is extremely widespread, with an estimated 8 percent to 10 percent of individuals in the United States 12 years of age or older (between ...

Because unpleasant withdrawal symptoms fuel nicotine addiction's high relapse rate, targeting their underlying mechanisms with treatments may promote continued abstinence from the drug. In a new ...

Remarkable scientific progress over the past five decades has helped us develop knowledge of how drugs of abuse induce pleasure, reinforce use, and lead to the compulsive self-administration we call ...

A preclinical study uncovered a new gene therapy that targets pain centers in the brain while eliminating the risk of ...

Cannabis Bioscience International Holdings, Inc. (OTCID: CBIH), a public company trading on the OTC Markets under the ticker ...

With growing interest in using psychedelic drugs to treat mental health disorders, researchers have explored the effects of a psychedelic derivative of amphetamine on rat brains. They wanted to see ...