Measuring CD4 T-cells is important in helping healthcare providers determine the stage and possible complications of HIV infection. While they are no longer used to determine when HIV therapy should ...

The ratio of CD4 to CD8 T cells in the blood-a marker of immune system health and associated with mortality risk in the general population-is an independent predictor of coronary heart disease in ...

Higher levels of CD4-positive naïve T cells in patients receiving CAR T-cell therapy for multiple myeloma are associated with ...

The decrease in CD4 cells during HIV infection seems to be driven by immune activation, which does not always correlate with viral load. Experienced clinicians are all too familiar with the ...

Figure 7: Proposed mode of action of INT-1B3/1B3. INT-1B3/1B3 induces apoptosis and cell death leading to expression of DAMPs, e.g., expression of calreticulin, reduced expression of CD39 and CD73 and ...

Most of these treatments are based on CD8 T lymphocytes, ''killer cells'' able to eliminate diseased cells. A team from the University of Geneva (UNIGE) has explored an alternative approach involving ...

Three days post viral infection CD8 T cells (red) re-arrest with antigen presenting cells (cyan), where they are supplied with IL-2 by CD4 T cells (yellow), which migrate in a stop and go pattern. The ...