Researchers have linked disease-related proteins and genes to identify specific cellular pathways responsible for Alzheimer's genesis and progression. The proteins were gathered from cerebrospinal ...

Using mass spectrometry, Emory University scientists have identified specific protein fingerprints in the cerebrospinal fluid (CSF) of humans that enable them to differentiate between cancers, both ...

Results showed CNS target engagement with reduction in GCase substrate glucosylsphingosine (GluSph) in cerebrospinal fluid (CSF), a prespecified ...

Exploring the genetic blueprint of cerebrospinal fluid proteins, this study uncovers new markers and therapeutic targets that may unlock advancements in Alzheimer’s diagnosis and care. Study: ...

A multitude of genes have been linked to the development of Alzheimer's disease. Specifically how those genes might influence the progression of neurodegeneration remains something of a black box ...

Faster motor and cognitive progression of Parkinson disease was found in patients with higher baseline cerebrospinal fluid neurofilament heavy levels. Higher cerebrospinal fluid (CSF) neurofilament ...

For many years, scientists have searched for the cause (or causes) of Alzheimer's disease. While a lot of research attention has focused on misfolded proteins as the potential culprit, there have been ...

“These exciting new data from coAAV-CSF-01 represent a major step forward in CNS gene therapy,” said Lolita Petit, CSO of Coave Therapeutics. “In non-human primates, the vector achieved robust brain ...