New mechanism found: Researchers discovered that statins can bind to and activate ryanodine receptors in muscle cells, potentially explaining muscle pain in some patients. Why it matters: Uncovering ...
Researchers engineered mice with a mutation (E3896A) in the RyR1 calcium-binding site, eliminating calcium-induced calcium release (CICR) without affecting depolarization-induced calcium release. The ...
New research has identified the specific biological mechanism behind the muscle dysfunction found in myotonic dystrophy type 1 (DM1) and further shows that calcium channel blockers can reverse these ...
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Inside the magic of muscle contraction
From your morning stretch to your fastest sprint, every movement depends on the precise dance between actin, myosin, and calcium inside your muscle fibers. Scientists are uncovering not only the ...
Biomedical engineers have grown muscles in a lab to better understand and test treatments for a group of extremely rare muscle disorders called dysferlinopathy or limb girdle muscular dystrophies 2B ...
We are at a critical time and supporting science journalism is more important than ever. Science News and our parent organization, the Society for Science, need your help to strengthen scientific ...
When most people hear “calcium,” they immediately think of strong bones and teeth. While this connection is certainly valid, calcium carbonate’s benefits extend far beyond skeletal support. This ...
The top row of photos show a microscopic view of healthy muscle fibers stained to reveal a variety of irregularities, while the bottom row shows the same but for muscle fibers afflicted by the disease ...
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