In many cancer types cathepsin proteases are upregulated and display altered trafficking and localization. Increased cathepsin expression generally correlates with increased malignancy and poor ...

Cathepsins are enzymes (known as proteases) that break down proteins. They play an important role in cell turnover, which is the process by which cells are replaced by young cells when older cells die ...

Scientists at the Walter Reed Army Institute for Research demonstrated the potential of a novel blood test for cathepsin B, a well-studied protein important to brain development and function, as an ...

Shanghai Yidian Pharmaceutical Technology Development Co. Ltd. has disclosed peptidyl nitrile compounds acting as cathepsin C (dipeptidyl peptidase I) inhibitors reported to be useful for the ...

TOKYO--(BUSINESS WIRE)--Alivexis, Inc. (headquartered in Tokyo, Japan, “Alivexis”) and Melodia Therapeutics AG (headquartered in Basel, Switzerland, “Melodia”), a company established by Forty51 ...

Researchers have identified a substance in muscles that helps explain the connection between a fit body and a sharp mind. When muscles work, they release a protein that appears to generate new cells ...

Insmed Inc. has divulged cathepsin C (dipeptidyl peptidase I, DPP1) inhibitors reported to be useful for the treatment of amyotrophic lateral sclerosis, asthma, metastatic cancer, chronic ...