DNA interactions lie at the heart of many biological processes and therapeutic strategies. Recent advances in spectroscopic, calorimetric and computational techniques have deepened our understanding ...
A new article analyzes in depth the physical problems associated with DNA packaging that have often been neglected in structural models of chromosomes. The study demonstrates that the multilaminar ...
Extrachromosomal DNA (ecDNA) is a unique form of circular DNA that exists outside of normal chromosomes. Found exclusively in tumor cells, it often carries cancer-promoting genes (oncogenes) and is ...
Scientists discover a 'Goldilocks' zone for DNA organization, opening new doors for drug development
In a discovery that could redefine how we understand cellular resilience and adaptability, scientists have unlocked the secret interactions between a primordial inorganic polymer of phosphate known as ...
Cancers begin with abnormal changes in individual cells, and the ability to track the accumulation of mutations at the single-cell level can shed new light on the early stages of the disease. Such ...
This Brush Up is sponsored by Cayman Chemical. Learn more about chemical inhibitors of histone modification. Histone modification affects how tightly DNA wraps around histone proteins, yielding ...
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