This study was conceived and guided by Prof. Ren Xiang Tan (Nanjing University). To tackle the challenging issues, the reaction flux derailing (RFD) approach was conceptualized, designed, and deployed ...
A fundamental challenge in drug development is the balance between optimizing a drug’s lock-and-key fit with its target and the drug’s ability to make its way across the cellular membrane and access ...
Randomized controlled trials have generally shown a benefit from accelerated radiotherapy in head and neck squamous cell carcinoma (HNSCC). However, the large randomized United Kingdom trial CHART ...
There is growing enthusiasm in the pharmaceutical industry for whole-system functional assays that reveal the action of potential drugs on integrated systems such as intact cells in order to find ...
A fundamental challenge in drug development is the balance between optimizing a drug's lock-and-key fit with its target and the drug's ability to make its way across the cellular membrane and access ...
A breakthrough in our understanding of mRNA delivery systems in the body may allow for more direct treatments for pancreas-related diseases, including cancer and diabetes. A new UNLV study by a team ...
CAMBRIDGE, Mass.--(BUSINESS WIRE)--Axcella (Nasdaq: AXLA), a clinical-stage biotechnology company pioneering a new approach to treat complex diseases and improve health using endogenous metabolic ...
In a recent study posted to the medRxiv* pre-print server, researchers from the UK quantified the levels of specialized pro-resolving molecules (SPMs) and pro-inflammatory bioactive lipids in the ...