The most frequent DNA lesions (8-oxoguanine, thymine glycol, dihydrothymine, dU) (De Bont and van Larebeke, 2014) are removed from the genome by the BER (Kim and Wilson, 2012) (Figure 1). This repair ...
DNA damage can occur spontaneously or be caused by mutagenic chemicals and physical factors such as radiation and sunlight. These modifications must be corrected to avoid detrimental effects to the ...