Background Lactate dehydrogenase (LDH) isoenzymes are required for adenosine triphosphate production, with each of five different isoenzymes having varying proficiencies in anaerobic versus aerobic ...

In clinical practice, lactate is a well-established tool for establishing diagnosis and prognosis in critically ill patients. 1 It can be used to diagnose sepsis and can also help in monitoring ...

For a long time, muscular fatigue during exercise was believed to be caused primarily by lactate as a by-product of glycolysis (glucose metabolism). In early studies, lactate was shown to increase in ...

Some past studies have shown that the biomarkers PD-1 and PD-L1 are associated with response to ICI treatment in NSCLC as well as PFS and OS. Authors of past studies have also suggested that ...

A new study on fulminant hepatic failure (FHF), a sudden and severe shutdown of the liver, examined ways of determining early on whether patients would benefit from a transplant as opposed to ...

Dynamic angiogenic switch as predictor of response to chemotherapy+ bevacizumab in patients with metastatic colorectal cancer. This is an ASCO Meeting Abstract from the 2016 ASCO Annual Meeting I.