Most obese patients grow resistant to satiety signals from the hormone leptin. A new study shows that leptin sensitivity can be restored in mice, leading to weight loss. Worldwide obesity rates have ...

Anil Oza is a general assignment reporter at STAT focused on the NIH and health equity. You can reach him on Signal at aniloza.16. The hormone leptin was discovered 30 years ago to much fanfare.

A team of scientists has uncovered a critical mechanism that could pave the way for safer and more effective obesity treatments. The findings, published in Nature Communications, shed light on how ...

Obesity has become a global epidemic affecting diverse populations and leading to metabolic syndrome across different sexes and age groups. A significant aspect of obesity is the development of leptin ...

Three decades ago, in a lab at The Rockefeller University, New York City, Jeffrey Friedman, MD, PhD, observed a paradox that would forever change our understanding of obesity. His subjects, a rare ...

Worldwide obesity rates have more than doubled since 1990, with nearly a billion people now falling into the category. Though a complex interplay of genes, diet, and environment contribute, 90% of ...

Those little fruit flies floating around the ripening cantaloupes pack some fat between their tiny wings. They’re cold-blooded and burn their fat to warm up. “They have really beautiful fat, the flies ...

Metabolic dysfunction-associated fatty liver disease (MAFLD) has emerged as a predominant chronic liver condition globally, intricately linked with obesity, type 2 diabetes (T2DM), and metabolic ...