The growth of tumors depends in part on its microenvironment, a dynamic area surrounding the tumor, which can include normal cells, supporting structures and molecules. Cancer cells can exert a major ...

Scientists at La Jolla Institute for Immunology (LJI) have discovered how a mutated gene kicks off a dangerous chain of events during blood cell production. "We know that many diseases—and all cancers ...

Whether they're damaged by injury or disease, or simply conducting the daily maintenance required for life, organisms have to make new cells. That generally requires replicating the organism's genome ...

Genomic Profiling Identifies Outcome-Relevant Mechanisms of Innate and Acquired Resistance to Third-Generation Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor Therapy in Lung Cancer The ...

A mutated gene affects growth of brain tumor cells in young adults, indicating sensitivity to a new treatment strategy, a team of researchers has discovered. These findings present possibilities for ...

Somatic Mutation PCR Testing Suppresses Amplification of Wild-Type Template DNA, Selectively Amplifies Mutant Templates In the context of personalized cancer treatment, the “gold standard” for tumor ...

Immunotherapy, which uses programmed immune cells to selectively destroy cancer cells, has transformed cancer treatment. However, cancer cells have developed immune evasion strategies, leading to poor ...

Advanced stage melanoma during pregnancy: Real-world management. This is an ASCO Meeting Abstract from the 2024 ASCO Annual Meeting I. This abstract does not include a full text component.

The protein complex cohesin is fundamental to the cell division process, as it holds sister chromatids tightly together in a ringlike structure before a cell physically splits. But now researchers at ...

How does a cell know when it’s been damaged? A molecular alarm, set off by mutated RNA and colliding ribosomes, signals danger. When the sun shines on your skin, what does it hit? When it causes a ...