Scientists have long known that some cells in a given tissue undergo a process of duplicating their entire genome without dividing – a process called endopolyploidy, where cellular ploidy is the copy ...
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Shining a spotlight on polyploid cells: New tool uncovers spatial patterns of DNA content across tissues
A collaborative effort by the Formosa-Jordan lab from the Max Planck Institute for Plant Breeding Research in Cologne, Germany, the Fox lab from Duke University, U.S., and the Roeder lab from Cornell ...
Assistant Professor of Biology Vicki Losick admits she harbors a desire to change the world a little bit. “I want to make ‘polyploidy’ a household word,” Losick said in her Higgins Hall office, next ...
(A) We created unique cells with double the usual number of chromosomes to investigate the relationship between polyploidy and DNA damage.(B) After treatment with the anti-cancer drug cisplatin, ...
Polyploidy is a state where a cell contains more copies of the genetic material than the usual "diploid" cell, which contains two copies. Polyploidy often occurs in human diseases and cancers, and its ...
Polyploidy is a state where a cell contains more copies of the genetic material than the usual "diploid" cell, which contains two copies. Polyploidy often occurs in human diseases and cancers, and its ...
Confocal microscopy is performed with nuclear reporters and stains, nuclear segmentation with ilastik is conducted, and a machine learning method is used to classify the ploidy of each nucleus. Colors ...
A collaborative effort by the Formosa-Jordan lab from the Max Planck Institute for Plant Breeding Research in Cologne, Germany, the Fox lab from Duke University, USA, and the Roeder lab from Cornell ...
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