AI maps fleeting DNA quadruplexes, revealing paired structures that control genes in healthy cells and cancer.

Researchers at the Centre for Genomic Regulation (CRG) reveal that metabolic enzymes known for their roles in energy production and nucleotide synthesis are taking on unexpected "second jobs" within ...

Researchers discovered that a long-misunderstood protein plays a key role in helping chromosomes latch onto the right “tracks” during cell division. Instead of acting like a motor, it works more like ...

An international research team has identified a human protein, ANKLE1, as the first DNA-cutting enzyme (nuclease) in mammals capable of detecting and responding to physical tension in DNA. This ...

New 3D genome maps reveal how DNA folding controls gene activity, offering fresh clues into disease and cell function.

Researchers have discovered how cells activate a last-resort DNA repair system when severe damage strikes. When genetic ...

Just one enzyme manages the refilling of the cellular soda machine that replicates our genes. PLK-1 initiates a process in two protein groups, leading to creation of new CENP-A proteins. These CENP-A ...

A new study published in Science Translational Medicine by researchers at The University of Texas MD Anderson Cancer Center ...

Although it also performs some functions in men, estrogen, the main female sex hormone, is involved in a myriad of processes, ...

Cancer’s most catastrophic DNA damage has long looked like a crime scene without a culprit, with chromosomes shattered and ...

Rb1 loss may serve as a predictive biomarker to guide new targeted therapies for select breast cancers resistant to standard ...