Synaptic dysfunction heralds cognitive and behavioral decline in neurodegenerative conditions such as Alzheimer’s and Parkinson’s diseases. Oligomers of Aβ, tau, and ɑ-synuclein may be to blame, but ...
A project at Rice University has developed a novel approach to nanoscale cellular imaging, one that could lead to improved knowledge of subcellular structures. Reported in Nature Communications, the ...
Even those who maintain that super-resolution microscopy is a powerful tool of biological discovery have admitted that it may have a bit of an image problem. For example, in a recent review, several ...
The Aplo Scope is a new single-molecule super-resolution microscope designed for molecular imaging. The microscope combines imaging, laser control, and what the company describes as intuitive software ...
In a study published in Nature Methods on December 2, a research team led by Profs. Xu Tao and Ji Wei from the Institute of ...
From left to right, Anna-Karin Gustavsson, Gabriella Gagliano and Nahima Saliba (Photo credit: Jeff Fitlow/Rice University). A team of researchers led by Anna-Karin Gustavsson at Rice University has ...
Existing super-resolution techniques still face considerable challenges in complex deep tissue environments. For example, Stimulated Emission Depletion (STED) microscopy relies on a doughnut-shaped ...
In a study published in Nature Methods on December 2, a research team led by Profs. XU Tao and JI Wei from the Institute of ...
Structured illumination microscopy (SIM) is the most preferable system for live-cell super-resolution imaging. It enables the observation of intricate subcellular dynamics. However, conventional SIM ...