Paroxysmal nocturnal hemoglobinuria (PNH) is a rare disorder that causes red blood cells to break down. This can lead to symptoms and complications ranging from discoloration of urine to leukemia and ...

Paroxysmal nocturnal hemoglobinuria (PNH) is an acquired, potentially life-threatening disorder linked to a specific gene. It can occur at any age but most often is diagnosed in young adults. PNH ...

Paroxysmal nocturnal hemoglobinuria (PNH) is a rare, progressive, multi-system, life-threatening disease, and diagnosing it early in the clinical course is essential for optimizing management ...

Paroxysmal nocturnal hemoglobinuria (PNH) is a rare blood disease in which the immune system breaks apart the red blood cells (RBCs) in the body. The medical term for this premature rupture of RBCs is ...

Clone size and symptom burden dictate how often patients with PNH require follow-up. Hematology assessments during routine visits should include flow cytometry, CBC, D-dimer levels, and serum ferritin ...

Paroxysmal nocturnal hemoglobinuria (PNH) is a rare and lethal disorder of the blood in which the body attacks and destroys red blood cells in massive amounts. This focus collection and short ...

If expansion of the PNH cell population takes place by virtue of selection in favor of the PIG-A mutant clone(s) in an aplastic environment, this mechanism might or might not still operate after the ...