What is Li-Fraumeni syndrome? Li-Fraumeni syndrome (LFS) is a genetic condition that increases the risk of developing many different types of cancers. What causes Li-Fraumeni syndrome? LFS is caused ...

GC ranks as the fifth most common and fourth deadliest cancer worldwide, presenting significant health challenges, particularly in China where it is most prevalent and accounts for nearly half of ...

In recent years, high-throughput technologies have provided unprecedented opportunities for analyzing cancer samples at multiple molecular levels. Each type of multi-omics dataset contributes to the ...

“The independent research groups, led by Prof. Scott W. Lowe and Christina Curtis,respectively, have uncovered a similar definitive pathway in the progression of gastric cancer (GC) initiated with ...

Among patients with chondrosarcomas, the most common primary bone tumor in adults, the presence of a TP53 gene mutation has been found to be associated with worse overall survival and metastasis-free ...

—A study of 1230 individuals with chronic lymphocytic leukemia and high-count monoclonal B-cell lymphocytosis demonstrated that patients with wild type TP53 had longer time to first treatment and ...