Cambridge, Mass.-based Akceli has been awarded a US patent for a reverse-transfection assay method (US patent 6,544,790, issued April 8, 2003). Akceli says the method condenses more than 6,000 data ...
Ever since the discovery of DNA’s double-helix structure, life scientists have been interested in somehow introducing foreign nucleic acid molecules into a host cell and expressing the genes encoded ...
Transfection, a key genetic technology in the toolbox of many researchers, spans numerous applications—production of recombinant proteins and recombinant cell lines, drug discovery, delivery of ...
To make the technique work in cultured mammalian cells, researchers must deliver small interfering RNAs (siRNAs), which are dsRNAs of 21-25 nucleotides, to the cell. They can use a wide range of ...
If you work in a lab, whether you are researching the cutting edge of cell and gene therapy development or running a simple molecular binding screen, the chances are you have done some transfection in ...
Hinnah Campwala (left) is a Principal Scientist in the Cell Biology Development Group at Sartorius BioAnalytical Instruments (Michigan, USA). With a background in drug discovery and immune cell ...
Accurate monitoring of nanoparticle size and growth is essential to ensure scalability in the development of transfection vectors for gene delivery. This study highlights how Spatially Resolved-DLS ...