A precancerous condition called Barrett’s oesophagus is of much interest, because it arises when some cells of the oesophagus take on a new identity — a phenomenon known as metaplasia. If we could ...

A shift in the balance between two lipids – cholesterol and sphingomyelin – makes hybrid epithelial-mesenchymal cancer cells less responsive to certain chemotherapy drugs.

KANSAS CITY, MO--Small-cell clones in proliferating epithelia - tissues that line all body surfaces - organize very differently than their normal-sized counterparts, according to a recent study from ...

To enable tissue renewal, human tissues constantly eliminate millions of cells, without jeopardizing tissue integrity, form and connectivity. The mechanisms involved in maintaining this integrity ...

Intercellular forces generate distinct patterns of extrusion: high compressive forces (top panel) drive apoptotic cell extrusion toward the upper side, while lower compressive forces (bottom panel) ...