Four years after its discovery, the weight-controlling protein hormone leptin is still making news. At the American Diabetes Association meeting in Chicago June 14, researchers from Amgen Inc. of ...

Obesity has become a global epidemic affecting diverse populations and leading to metabolic syndrome across different sexes and age groups. A significant aspect of obesity is the development of leptin ...

Anil Oza is a general assignment reporter at STAT focused on the NIH and health equity. You can reach him on Signal at aniloza.16. The hormone leptin was discovered 30 years ago to much fanfare.

NEW YORK – New research from Columbia University Medical Center has illuminated a previously unknown leptin-serotonin pathway in the brain that simultaneously promotes appetite and bone mass accrual.

Scientists at Pennington Biomedical Research Center have gained greater clarity in the brain regions and neurons that control metabolism, body temperature and energy use. Featured in the February ...

A study more closely links obesity to dementia, finding that leptin, a hormone that helps maintain normal body weight, is associated with better signal-transmitting brain white matter in middle-aged ...

There's no doubt that you can lose fat by eating less or moving more--yet after decades of research, the biology underlying this equation remains mysterious. What really ignites the breakdown of ...

"This work provides the first example of how leptin can regulate the presence of neurons in fat, both white and brown," adds Cohen. Through this pathway, fat appears to be telling the brain how much ...

Forbes contributors publish independent expert analyses and insights. Questions about hunger and fullness come up constantly in my clinic. Many patients try to manage appetite through willpower alone, ...