The 49ers beat the Colts on Monday night at Lucas Oil Stadium, and after the game, Kyle Shanahan was especially proud of two ...

San Francisco 49ers running back Christian McCaffrey now has 3,446 rushing yards with the team, putting him 10th in franchise ...

The San Francisco 49ers may have one of their top offensive weapons available after an injury took him out of Week 16.

The Chamber Music Society of Palm Beach has chosen performers for its intensive chamber music program's second season in ...

San Francisco 49ers quarterback Brock Purdy threw five touchdowns against the Indianapolis Colts on Monday, earning NFC Offensive Player of the Week.

A fire was reported at Silver Lake Healthcare Center on Dec. 23 with some nearby residents saying they heard an explosion and ...

Two Columbus sisters say they were threatened after following vehicles they believed belonged to ICE, an act that is not ...

The San Francisco 49ers offense is cruising and they were dominant in a win over the Indianapolis Colts. Here are the ...

Week 16 was a great week for the San Francisco 49ers, who clinched a playoff berth and moved up in both the division and ...

The San Francisco 49ers downed the Indianapolis Colts on Monday night, and here's who deserves credit and criticism.

The 49ers may have offensive tackle Trent Williams around for longer than expected after his comments following their win ...

The San Francisco 49ers may have to navigate a couple of games without one of their superstars, but he avoided a longer-term ...