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  1. Adstiladrin: Uses, Dosage, Side Effects & Warnings - Drugs.com

    Dec 9, 2024 · Adstiladrin is a prescription gene therapy used for the treatment of a certain type of bladder cancer. Adstiladrin contains nadofaragene firadenovec-vncg, a non-replicating …

  2. Bladder Cancer Treatment Options

    ADSTILADRIN is a non-replicating adenoviral vector-based gene therapy indicated for the treatment of adult patients with high-risk Bacillus Calmette-Guérin (BCG)-unresponsive non …

  3. Clinical overview Indication: ADSTILADRIN® (nadofaragene firadenovec-vncg) is a non-replicating adenoviral vector-based gene therapy indicated for the treatment of adult patients …

  4. First Bladder Cancer Patient Dosed with Commercially Available ...

    Sep 12, 2023 · ADSTILADRIN ® (nadofaragene firadenovec-vncg) is the first and only FDA-approved intravesical gene therapy for the treatment of adult patients with high-risk Bacillus …

  5. Nadofaragene firadenovec uses a recombinant adenovirus that encodes for interferon alpha-2b gene. Intravesical instillation of interferon alone for bladder cancer produced complete …

  6. ADSTILADRIN® is indicated for the treatment of adult patients with high-risk Bacillus Calmette-Guérin (BCG)-unresponsive non-Muscle Invasive Bladder Cancer (NMIBC) with carcinoma in …

  7. The Current Treatment Landscape of BCG-unresponsive Non …

    FDA D.I.S.C.O. Burst Edition: FDA approval of Adstiladrin (nadofaragene firadenovec-vncg) for patients with high-risk Bacillus Calmette-Gu√©rin unresponsive non-muscle invasive bladder …

  8. FDA Approval Summary: Nadofaragene Firadenovec-vncg for …

    Apr 1, 2025 · Abstract On December 16, 2022, the FDA approved the adenoviral vector-based gene therapy nadofaragene firadenovec-vncg (brand name Adstiladrin) for the treatment of …

  9. Nov 12, 2025 · Gene therapy works by delivering helpful genetic material directly into the bladder to fight cancer cells and boost the body’s immune response. Three gene therapies (nado …

  10. Nadofaragene Firadenovec-vncg - NCI - National Cancer Institute

    Nadofaragene firadenovec-vncg is approved to treat: Non-muscle–invasive bladder cancer with carcinoma in situ. It is used in adults whose cancer does not respond to treatment with bacillus …