Pyroptosis is a highly inflammatory form of lytic programmed cell death that occurs most frequently upon infection with intracellular pathogens and is likely to form part of the …

2 days ago · Pyroptosis exhibits dual therapeutic advantages by remodeling the tumor microenvironment and potentiating systemic anti-tumor immunity, positioning it as a pivotal …

Pyroptosis is a lytic and inflammatory type of programmed cell death that is usually triggered by inflammasomes and executed by gasdermin proteins. The main characteristics of pyroptosis …

Jul 20, 2025 · Pyroptosis is a type of programmed cell death that is part of the body’s immune response to intracellular pathogens. It is a highly inflammatory process that acts as a cellular …

Pyroptosis is defined as a distinct form of regulated cell death that plays a crucial role in protecting cells from infection by microbial pathogens, characterized by the rupture of the cell membrane …

Apr 3, 2025 · Pyroptosis is a type of programmed necrosis triggered by the detection of pathogens or endogenous danger signals in the cytosol. Pyroptotic cells exhibit a swollen, …

This review explores the history of pyroptosis, recent insights into gasdermin activation, the cellular consequences of pore formation, and the physiological roles of pyroptosis.

Sep 16, 2022 · The term pyroptosis, derived from the Greek roots pyro (fire/fever) and ptosis (to-sis, falling), was first proposed by D’Souza et al. in 2001 to define this inflammatory cell death (9).

Jul 31, 2025 · Pyroptosis is a specific type of programmed cell death characterized by a highly inflammatory response. It actively promotes inflammation through the release of cellular …

Sep 20, 2024 · Pyroptosis is a type of programmed cell death characterized by cell swelling and osmotic lysis, resulting in cytomembrane rupture and release of immunostimulatory …