Telomere - Wikipedia
Human chromosomes (grey) capped by telomeres (white) A telomere (/ ˈtɛləmɪər, ˈtiːlə -/; from Ancient Greek τέλος (télos) 'end' and μέρος (méros) 'part') is a region of repetitive nucleotide …
What Are Telomeres and Why Do They Matter in Aging?
Aug 4, 2025 · The Telomere Clock: Ticking Toward Cellular Aging The telomere’s role in aging becomes clear when you realize they’re not endlessly replenished. In most somatic (body) …
Telomere
3 days ago · A telomere is a region of repetitive DNA sequences at the end of a chromosome. Telomeres protect the ends of chromosomes from becoming frayed or tangled. Each time a …
Are Telomeres the Key to Aging and Cancer - University of Utah
While telomere shortening has been linked to the aging process, it is not yet known whether shorter telomeres are just a sign of aging like gray hair or actually contribute to aging. If …
Telomeres and Telomerase: Structure and Functions
Mar 30, 2025 · Telomeres are the structure of nucleoproteins that are present at the end of chromosomes in eukaryotes. These telomeres are similar to the cap that preserves the …
Telomere | DNA Segment, Chromosome Protection | Britannica
Nov 20, 2025 · Telomere, segment of DNA occurring at the ends of chromosomes in eukaryotic cells (cells containing a clearly defined nucleus). Telomeres are made up of repeated …
Telomeres: The Role of Shortening in Cancer and Aging, How to …
Mar 8, 2019 · Telomeres are small structures that protect the ends of your chromosomes. Over time, they tend to get shorter. We’ll dive into the recent research surrounding telomere …
Telomeres and Telomere Length: A General Overview - PMC
Telomere shortening, therefore, acts as a counting mechanism that drives replicative senescence by limiting the mitotic potential of cells. Telomere length, a complex hereditary trait, is …
Telomere function and regulation from mouse models to human …
Nov 29, 2024 · Telomere dysfunction, usually owing to shortening, activates cellular senescence and can contribute to age-associated diseases and cancer. Mouse models are crucial for …
Telomeres: Function, Role in Aging, and Impact on Health
Telomeres and telomerase also play a role in cancer development. While telomere shortening normally acts as a tumor-suppressive mechanism by limiting cell division, cancer cells often …
Center for Individualized Medicine - Telomere Biology Disorders
The Telomere Translational Program has established functional testing workflows to test most of these variants. Clinical significance of somatic mosaic states in telomere biology disorders. …
Telomeres: Structure and Function - Springer
Mar 22, 2023 · Telomeres are specialized, highly conserved DNA-protein complexes at the ends of linear eukaryotic chromosomes. Human telomeric DNA is composed of tandem repeats of …